Adjuvant polyarthritis I: incorporation of quantitative measurements of humoral and cellular immune response.
نویسنده
چکیده
A modified model of adjuvant arthritis is described that permits simultaneous quantitative measurement of the humoral and the cellular immune response to a secondary immunogen (el4 cells) in the arthritic rat. Application of the new model system to mechanism studies is illustrated with cyclophosphamide. The drug is shown to suppress adjuvant arthritis by a combined anti-inflammatory and immunosuppressive action.
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ورودعنوان ژورنال:
- The Journal of pharmacology and experimental therapeutics
دوره 201 1 شماره
صفحات -
تاریخ انتشار 1977